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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saji, Yutaka | SP | New Mexico Aztecs | 17 | 09/30/1988 | Nagano | JPN | Left | Left | 6' 3" | 180 lbs | - |
| Sakal, Max | RP | Baton Rouge Red Sticks | 21 | 11/05/1984 | Phoenix | USA | Left | Left | 6' 7" | 195 lbs | - |
| Sakamoto, Korenaga | RP | New Mexico Aztecs | 19 | 05/10/1986 | Tokyo | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Sanchez, Victor | RP | Charlottesville Cavaliers | 20 | 04/28/1985 | Managua | NCA | Right | Right | 6' 6" | 190 lbs | - |
| Sanders, Zach | RF | El Paso Diablos | 20 | 09/17/1985 | North Potomac | USA | Left | Left | 6' 2" | 195 lbs | - |
| Santagata, Joe | SS | Gainesville Sharks | 22 | 06/27/1983 | Granite City | USA | Right | Right | 6' 3" | 190 lbs | - |
| Santos, Pedro | 3B | Baton Rouge Red Sticks | 22 | 09/27/1983 | Lodi | USA | Right | Right | 5' 10" | 185 lbs | - |
| Schaffer, Nick | 3B | Huntsville Rocketeers | 20 | 11/26/1985 | Richmond | USA | Right | Right | 6' 3" | 195 lbs | - |
| Scott, Will | RP | Fort Worth Cowboys | 22 | 04/27/1983 | San Diego | USA | Left | Left | 6' 1" | 170 lbs | - |
| Sholar, Kevin | RF | Charlottesville Cavaliers | 20 | 12/18/1985 | Upland | USA | Right | Right | 6' 5" | 200 lbs | - |
| Sierra, Brian | LF | Ogden Trappers | 21 | 11/04/1984 | Scottsdale | USA | Right | Right | 6' 0" | 190 lbs | - |
| Sifuentes, Edwin | C | Rochester Roosters | 21 | 09/29/1984 | Arica | CHI | Right | Right | 5' 10" | 170 lbs | - |
| Silvas, Antonio | SP | Gainesville Sharks | 21 | 05/16/1984 | Levittown | PUR | Right | Right | 6' 3" | 180 lbs | - |
| Silverman, Roger | 2B | Gainesville Sharks | 21 | 04/06/1984 | Munich | GER | Right | Right | 6' 1" | 195 lbs | - |
| Simmons, Sheldon | SP | Smokey Mountain 'Shiners | 22 | 07/27/1983 | San Diego | USA | Right | Right | 6' 1" | 185 lbs | - |
| Smith, Mike | LF | Smokey Mountain 'Shiners | 20 | 02/21/1985 | Victoria | USA | Right | Right | 6' 2" | 195 lbs | - |
| Smith, Paul | SP | Charlottesville Cavaliers | 19 | 06/02/1986 | Pilot Butte | CAN | Right | Right | 6' 6" | 200 lbs | - |
| Smith, Rusty | SP | El Paso Diablos | 20 | 09/05/1985 | Toledo | USA | Right | Right | 6' 6" | 205 lbs | - |
| Snow, Jesse | LF | Smokey Mountain 'Shiners | 20 | 11/22/1985 | San Diego | USA | Left | Right | 6' 3" | 185 lbs | - |
| Sorber, Pete | SP | Gainesville Sharks | 21 | 09/18/1984 | Los Angeles | USA | Right | Right | 6' 1" | 185 lbs | - |
| Souders, Billy | C | Maine Lobsters | 20 | 03/29/1985 | Grantsville | USA | Switch | Right | 6' 6" | 205 lbs | - |
| Spall, Caiden | 1B | Smokey Mountain 'Shiners | 22 | 07/25/1983 | Brockton | USA | Right | Right | 5' 11" | 185 lbs | - |
| Sparks, Bobby | SP | Lincoln Larks | 20 | 03/18/1985 | Gallipolis | USA | Right | Right | 6' 4" | 190 lbs | - |
| Sparks, Josh | RP | Gainesville Sharks | 22 | 06/13/1983 | Seabrook | USA | Left | Right | 6' 3" | 185 lbs | - |
| Spero, Eddie | CL | El Paso Diablos | 22 | 11/19/1983 | Kentfield | USA | Right | Right | 5' 10" | 180 lbs | - |
| St. Vincent, Glenn | CF | Maine Lobsters | 22 | 09/21/1983 | Huntington | USA | Left | Left | 6' 5" | 200 lbs | - |
| Stoermer, Joe | 2B | Smokey Mountain 'Shiners | 22 | 12/27/1983 | Reno | USA | Right | Right | 6' 0" | 190 lbs | - |
| Stoner, John | C | El Paso Diablos | 21 | 08/10/1984 | Tell City | USA | Right | Right | 5' 11" | 180 lbs | - |
| Stovall, Eric | SP | Quebec Blues | 20 | 07/20/1985 | Austin | USA | Right | Right | 6' 1" | 175 lbs | - |
| Streets, Neal | C | Smokey Mountain 'Shiners | 21 | 02/01/1984 | Brooklyn | USA | Left | Right | 6' 0" | 185 lbs | - |
| Stringfellow, Wayne | C | Gainesville Sharks | 21 | 09/06/1984 | Coralville | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Sullins, Chris | SP | Charlottesville Cavaliers | 20 | 10/09/1985 | Largo | USA | Right | Right | 6' 4" | 185 lbs | - |
| Sullivan, Pat | CF | Chicago Cardinals | 20 | 04/05/1985 | Freeport | USA | Right | Left | 5' 10" | 175 lbs | - |
| Sunaga, Yuu | RP | El Paso Diablos | 20 | 01/18/1985 | Seiro | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Swinson, Nick | RP | Baton Rouge Red Sticks | 22 | 11/04/1983 | Boise | USA | Right | Right | 6' 3" | 180 lbs | - |
