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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakal, Max | SP | Baton Rouge Red Sticks | 20 | 11/05/1984 | Phoenix | USA | Left | Left | 6' 7" | 195 lbs | - |
| Sakamoto, Korenaga | RP | New Mexico Aztecs | 18 | 05/10/1986 | Tokyo | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Salazar, Reynaldo | RP | Colorado Springs 14ers | 18 | 04/30/1986 | Buenaventura | COL | Right | Right | 6' 1" | 180 lbs | - |
| Sanchez, Jose | SP | Worcester Hearts | 17 | 06/05/1987 | Holguín | CUB | Left | Right | 6' 4" | 185 lbs | - |
| Sanchez, Victor | RP | DC Potomacs | 19 | 04/28/1985 | Managua | NCA | Right | Right | 6' 6" | 190 lbs | - |
| Sanders, Zach | CF | Lincoln Larks | 19 | 09/17/1985 | North Potomac | USA | Left | Left | 6' 2" | 190 lbs | - |
| Saragosa, Jeremy | RP | New Mexico Aztecs | 19 | 12/11/1985 | Waterloo | USA | Right | Right | 6' 4" | 190 lbs | - |
| Sbarro, Jose | RP | Smokey Mountain 'Shiners | 19 | 10/10/1985 | Turmero | VEN | Right | Right | 6' 0" | 170 lbs | - |
| Scaggs, Charles | RP | Colorado Springs 14ers | 18 | 03/28/1986 | Cedar Grove | USA | Right | Right | 6' 4" | 180 lbs | - |
| Schaffer, Nick | 3B | Huntsville Rocketeers | 19 | 11/26/1985 | Richmond | USA | Right | Right | 6' 3" | 200 lbs | - |
| Sehl, Paul | 1B | Dayton Aviators | 19 | 09/25/1985 | Sedalia | USA | Right | Right | 6' 2" | 195 lbs | - |
| Sera, Takiji | RP | Smokey Mountain 'Shiners | 17 | 01/15/1987 | Isshiki | JPN | Right | Right | 6' 4" | 185 lbs | - |
| Serrata, Federico | CF | Rochester Roosters | 18 | 10/14/1986 | Ponce | PUR | Right | Right | 6' 2" | 180 lbs | - |
| Shand, Samuel | SP | Worcester Hearts | 18 | 09/18/1986 | Grove Place | VIR | Switch | Right | 6' 5" | 200 lbs | - |
| Sigmund, Tommy | 3B | Baton Rouge Red Sticks | 19 | 10/02/1985 | Baytown | USA | Right | Right | 6' 3" | 185 lbs | - |
| Siu, Zhu-lan | RP | Smokey Mountain 'Shiners | 19 | 06/29/1985 | Taipei | TPE | Right | Right | 6' 8" | 195 lbs | - |
| Slack, Chris | CL | Fort Worth Cowboys | 19 | 08/28/1985 | Allendale | USA | Right | Left | 6' 2" | 165 lbs | - |
| Slob, Maarten | SP | Dayton Aviators | 19 | 09/03/1985 | Aalten | NED | Right | Right | 6' 0" | 175 lbs | - |
| Smith, Mike | LF | Smokey Mountain 'Shiners | 19 | 02/21/1985 | Victoria | USA | Right | Right | 6' 2" | 195 lbs | - |
| Soriano, David | C | Smokey Mountain 'Shiners | 19 | 07/09/1985 | Ponce | PUR | Right | Right | 6' 3" | 200 lbs | - |
| Souders, Billy | C | Worcester Hearts | 19 | 03/29/1985 | Grantsville | USA | Switch | Right | 6' 6" | 200 lbs | - |
| Spagnolo, Ted | SP | Worcester Hearts | 18 | 01/20/1986 | Honea Path | USA | Left | Right | 5' 8" | 150 lbs | - |
| Spicer, Ken | LF | Worcester Hearts | 19 | 05/23/1985 | Borger | USA | Left | Right | 6' 5" | 200 lbs | - |
| Spikes, Ryan | SS | Worcester Hearts | 18 | 02/15/1986 | Elizabeth | USA | Right | Right | 6' 1" | 170 lbs | - |
| Stanek, Ray | RP | New Mexico Aztecs | 19 | 07/07/1985 | Bell Gardens | USA | Right | Right | 6' 6" | 200 lbs | - |
| Steele, Jude | CL | Baton Rouge Red Sticks | 19 | 06/14/1985 | May Pen | JAM | Right | Right | 6' 2" | 185 lbs | - |
| Stilger, Bobby | LF | Fort Worth Cowboys | 18 | 06/13/1986 | Hueytown | USA | Right | Right | 6' 1" | 180 lbs | - |
| Stovall, Eric | SP | Free Agent | 19 | 07/20/1985 | Austin | USA | Right | Right | 6' 1" | 175 lbs | - |
| Sullivan, Pat | CF | Chicago Fire Dogs | 19 | 04/05/1985 | Freeport | USA | Right | Left | 5' 10" | 170 lbs | - |
| Sunaga, Yuu | RP | Lincoln Larks | 19 | 01/18/1985 | Seiro | JPN | Right | Right | 6' 1" | 170 lbs | - |
| Sundermeyer, Larry | SP | Huntsville Rocketeers | 18 | 04/28/1986 | Hot Springs | USA | Left | Left | 6' 0" | 160 lbs | - |
| Suzuki, Nobumasa | C | Smokey Mountain 'Shiners | 19 | 10/02/1985 | Hachinohe | JPN | Switch | Right | 6' 1" | 195 lbs | - |
