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| Sunday, November 27th , 2022 |
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| Fired Manager John Clyne. |
| Pitching Coach Kylian Dufour signed as Manager in Hartford. |
| Signed Manager Kylian Dufour. |
| Tuesday, November 1st , 2022 |
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| Fired Manager Mike Valencia. |
| Signed Manager John Clyne. |
| Sunday, October 30th , 2022 |
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| Drafted 1B Carl Turnbull in the 2022 first-year player draft (Round 2, Pick 8, 26th overall pick). |
| Drafted 3B Luis Aguilar in the 2022 first-year player draft (Round 5, Pick 8, 80th overall pick). |
| Drafted 2B Fabian Rendon in the 2022 first-year player draft (Round 14, Pick 14, 296th overall pick). |
| Monday, September 5th , 2022 |
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| Fired Pitching Coach Jack McAuley. |
| Signed Pitching Coach Jon Person. |
| Monday, May 2nd , 2022 |
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| Promoted RF Gianfrancesco Bracco to Major League Boston. |
| Promoted RF Nelson Amador to Major League Boston. |
| Promoted 3B Fernando Rivera to Major League Boston. |
| Promoted LF Carlos Espada to Major League Boston. |
