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| Saturday, October 30th , 2021 |
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| Drafted C Jack Parsons in the 2021 first-year player draft (Round 5, Pick 6, 78th overall pick). |
| Drafted C Chris Wamack in the 2021 first-year player draft (Round 17, Pick 6, 294th overall pick). |
| Tuesday, October 19th , 2021 |
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| CF Justin Martin retired from professional baseball. |
| 1B Kanne Weber retired from professional baseball. |
| Sunday, May 2nd , 2021 |
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| Promoted SP Guillermo Tulk to Major League Boston. |
| Promoted RF Gianfrancesco Bracco to Major League Boston. |
| Promoted SS David Miles to Major League Boston. |
| Promoted C René Monnier to Major League Boston. |
