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| Tuesday, November 19th , 2019 |
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| RP Bob Vroom becomes a free-agent. |
| Wednesday, October 30th , 2019 |
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| Drafted CF Jim McArdle in the 2019 first-year player draft (Round 10, Pick 11, 173rd overall pick). |
| Wednesday, May 1st , 2019 |
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| Promoted RP T.J. Jones to Major League St. Louis. |
| Promoted RP Corey Jones to Major League St. Louis. |
| Promoted RP Eikki Joenlahti to Major League St. Louis. |
| Promoted RP Adam Lonzo to Major League St. Louis. |
| Promoted C Jayden Scott to Major League St. Louis. |
| Promoted SP George Spence to Major League St. Louis. |
| Promoted LF Karl Bruno to Major League St. Louis. |
| Promoted 3B John Wright to Major League St. Louis. |
| Promoted SS Edgar Perez to Major League St. Louis. |
| Monday, February 4th , 2019 |
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| Received 3B Doug Yahn from Major League St. Louis. |
| Received LF Caetano Chapelas from Major League St. Louis. |
