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| Monday, November 1st , 2010 |
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| Signed Hitting Coach Jose Greathouse. |
| Thursday, October 21st , 2010 |
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| RF Brandon Clow retired from professional baseball. |
| Saturday, May 1st , 2010 |
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| Promoted 3B Mike Sinko to Major League San Francisco. |
| Promoted RP Tim Bommer to Major League San Francisco. |
| Promoted SP J.J. Vassey to Major League San Francisco. |
| Promoted CF Jared Marsh to Major League San Francisco. |
| Promoted RF Dan Garner to Major League San Francisco. |
| Promoted SS Shawn Spruiell to Major League San Francisco. |
